Super-resolution imaging of C-type lectin spatial rearrangement within the dendritic cell plasma membrane at fungal microbe contact sites

Dendritic cells express DC-SIGN and CD206, C-type lectins (CTLs) that bind a variety of pathogens and may facilitate pathogen uptake for subsequent antigen presentation. Both proteins form punctate membrane nanodomains (~80 nm) on naïve cells. We analyzed the spatiotemporal distribution of CTLs foll...

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Bibliographic Details
Main Authors: Michelle S Itano, Matthew S Graus, Carolyn ePehlke, Michael J Wester, Ping eLiu, Keith A Lidke, Nancy L Thompson, Ken eJacobson, Aaron K Neumann
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Physics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphy.2014.00046/full