High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow

High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow

Abstract Background Cancer is a complex, multiscale dynamical system, with interactions between tumor cells and non-cancerous host systems. Therapies act on this combined cancer-host system, sometimes with unexpected results. Systematic investigation of mechanistic computational models can augment t...

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Bibliographic Details
Main Authors: Jonathan Ozik, Nicholson Collier, Justin M. Wozniak, Charles Macal, Chase Cockrell, Samuel H. Friedman, Ahmadreza Ghaffarizadeh, Randy Heiland, Gary An, Paul Macklin
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
Agent-based model
PhysiCell
Cancer
Immunotherapy
High throughput computing
EMEWS
Online Access:http://link.springer.com/article/10.1186/s12859-018-2510-x

Internet

http://link.springer.com/article/10.1186/s12859-018-2510-x

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