An Adsorptive Transfer Technique Coupled with Brdicka Reaction to Reveal the Importance of Metallothionein in Chemotherapy with Platinum Based Cytostatics

An Adsorptive Transfer Technique Coupled with Brdicka Reaction to Reveal the Importance of Metallothionein in Chemotherapy with Platinum Based Cytostatics

The drugs based on platinum metals represent one of the oldest, but also one of the most effective groups of chemotherapeutic agents. Thanks to many clinical studies it is known that resistance of tumor cells to drugs is a frequent cause of chemotherapy failure. With regard to platinum based drugs,...

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Bibliographic Details
Main Authors: Libuse Trnkova, Rene Kizek, Richard Prusa, Denisa Darsova, Jiri Kukacka, Tomas Eckschlager, Pavel Pochop, Jan Hrabeta, Petr Babula, Vojtech Adam, Dalibor Huska, Ivo Fabrik, Sona Krizkova
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:International Journal of Molecular Sciences
Subjects:
tumor disease
metallothionein
platinum based anticancer drugs
anticancer therapy
resistance
retinoblastoma
Online Access:http://www.mdpi.com/1422-0067/11/12/4826/

Internet

http://www.mdpi.com/1422-0067/11/12/4826/

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