Retinoic Acid signalling and the control of meiotic entry in the human fetal gonad.

The development of mammalian fetal germ cells along oogenic or spermatogenic fate trajectories is dictated by signals from the surrounding gonadal environment. Germ cells in the fetal testis enter mitotic arrest, whilst those in the fetal ovary undergo sex-specific entry into meiosis, the initiation...

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Bibliographic Details
Main Authors: Andrew J Childs, Gillian Cowan, Hazel L Kinnell, Richard A Anderson, Philippa T K Saunders
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108594?pdf=render