Sensitive determination of 4-O-methylhonokiol in rabbit plasma by high performance liquid chromatography and application to its pharmacokinetic investigation

A novel high Performance liquid Chromatographie method was developed for the determination of 4-O-methylhonokiol in rabbit plasma and was applied to its pharmacokinetic investigation. Plasma samples were treated by one-fold volume of methanol and acetonitrile to remove the interference proteins. A r...

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Bibliographic Details
Main Authors: Ming-Yue Li, Yu-Hai Tang, Xia Liu, Hai-Yan Lü, Xi-Yan Shi
Format: Article
Language:English
Published: Elsevier 2011-05-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177911700193