Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

<p>Abstract</p> <p>Background</p> <p>Human papillomavirus (HPV) vaccines based on major capsid protein L1 are licensed in over 100 countries to prevent HPV infections. The yeast-derived recombinant quadrivalent HPV L1 vaccine, GARDASIL(R), has played an important role i...

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Bibliographic Details
Main Authors: Zhao Qinjian, Modis Yorgo, High Katrina, Towne Victoria, Meng Yuan, Wang Yang, Alexandroff Jaime, Brown Martha, Carragher Bridget, Potter Clinton S, Abraham Dicky, Wohlpart Dave, Kosinski Mike, Washabaugh Mike W, Sitrin Robert D
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Virology Journal
Subjects:
Recombinant subunit vaccine
Virus-like particle (VLP)
Neutralizing monoclonal antibody
Redox treatment
Competitive fluorescence ELISA
Epitope mapping
Atomic homology model
Online Access:http://www.virologyj.com/content/9/1/52

Internet

http://www.virologyj.com/content/9/1/52

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