Epimutation and Cancer: Carcinogenesis Viewed as Error-Prone Inheritance of Epigenetic Information
The epimutation concept, that is, malignancy is a result of deranged patterns of gene expression due to defective epigenetic control, proposes that in the majority of adult cancers the primary (initiating) lesion adversely affects the mechanism of vertical transmission of the epigenetic pattern exis...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2018-01-01
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| Series: | Journal of Oncology |
| Online Access: | http://dx.doi.org/10.1155/2018/2645095 |