A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.

A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.

Human natural killer-1 (HNK-1) carbohydrate (HSO3-3GlcAβ1-3Galβ1-4GlcNAc-R) is highly expressed in the brain and required for learning and neural plasticity. We previously demonstrated that expression of the HNK-1 epitope is mostly abolished in knockout mice for GlcAT-P (B3gat1), a major glucuronylt...

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Bibliographic Details
Main Authors: Keiko Yabuno, Jyoji Morise, Yasuhiko Kizuka, Noritaka Hashii, Nana Kawasaki, Satoru Takahashi, Shinji Miyata, Tomomi Izumikawa, Hiroshi Kitagawa, Hiromu Takematsu, Shogo Oka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686076?pdf=render

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http://europepmc.org/articles/PMC4686076?pdf=render

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