Efficacy and safety of bempedoic acid alone or combining with other lipid-lowering therapies in hypercholesterolemic patients: a meta-analysis of randomized controlled trials

Efficacy and safety of bempedoic acid alone or combining with other lipid-lowering therapies in hypercholesterolemic patients: a meta-analysis of randomized controlled trials

Abstract Background Bempedoic acid is a new drug that reduces cholesterol synthesis via inhibiting ATP citrate lyase. It remains unclear whether the combination of bempedoic acid and other lipid-lowering drugs is better than these drugs alone. This study systematically reviewed the efficacy and safe...

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Bibliographic Details
Main Authors: Xiang Zhao, Xubiao Ma, Xing Luo, Zhihua Shi, Ziwen Deng, Yuanxiang Jin, Zhipeng Xiao, Liming Tan, Pingfang Liu, Shilong Jiang, Yuanglu Shu, Bing Tang, Chengfeng Qiu
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Pharmacology and Toxicology
Subjects:
Bempedoic acid
Statin
Ezetimibe
Low-density lipoprotein cholesterol
Adverse events
Meta-analysis
Online Access:https://doi.org/10.1186/s40360-020-00463-w

Internet

https://doi.org/10.1186/s40360-020-00463-w

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