Functional polymorphisms and transcriptional analysis in the 5′ region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders

Abstract Background The 5-hydroxytryptamine 1B receptor (5-HT1B) plays an essential role in the serotonin (5-HT) system and is widely involved in a variety of brain activities. HTR1B is the gene encoding 5-HT1B. Genome-wide association studies have shown that HTR1B polymorphisms are closely related...

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Bibliographic Details
Main Authors: Xi Xia, Mei Ding, Jin-feng Xuan, Jia-xin Xing, Jun Yao, Xue Wu, Bao-jie Wang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-020-02906-4