Inhibition of NADPH oxidase alleviates germ cell apoptosis and ER stress during testicular ischemia reperfusion injury

Inhibition of NADPH oxidase alleviates germ cell apoptosis and ER stress during testicular ischemia reperfusion injury

Testicular torsion and detorsion (TTD) is a serious urological condition affecting young males that is underlined by an ischemia reperfusion injury (tIRI) to the testis as the pathophysiological mechanism. During tIRI, uncontrolled production of oxygen reactive species (ROS) causes DNA damage leadin...

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Bibliographic Details
Main Authors: Farah Al-Saleh, Farah Khashab, Fatemah Fadel, Nora Al-Kandari, May Al-Maghrebi
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Saudi Journal of Biological Sciences
Subjects:
Testicular ischemia Reperfusion Injury
NADPH oxidase
Oxidative stress
Germ cell apoptosis
ER stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X20301364

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http://www.sciencedirect.com/science/article/pii/S1319562X20301364

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