Aortic acceleration as a noninvasive index of left ventricular contractility in the mouse
Abstract The maximum value of the first derivative of the invasively measured left ventricular (LV) pressure (+ dP/dtmax or P′) is often used to quantify LV contractility, which in mice is limited to a single terminal study. Thus, determination of P′ in mouse longitudinal/serial studies requires a g...
Main Authors: | Jorge Enrique Tovar Perez, Jesus Ortiz-Urbina, Celia Pena Heredia, Thuy T. Pham, Sridhar Madala, Craig J. Hartley, Mark L. Entman, George E. Taffet, Anilkumar K. Reddy |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-79866-y |
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