Fluorescence in Situ Hybridization (FISH) for Detecting Anaplastic Lymphoma Kinase (<i>ALK</i>) Rearrangement in Lung Cancer: Clinically Relevant Technical Aspects

In 2011, the Vysis Break Apart ALK fluorescence in situ hybridization (FISH) assay was approved by the United States Food and Drug Administration as a companion diagnostic for detecting <i>ALK</i> rearrangement in lung cancer patients who may benefit from treatment of tyrosine kinase inh...

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Bibliographic Details
Main Authors: Zhenya Tang, Lu Wang, Guilin Tang, L. Jeffrey Medeiros
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
ALK
Online Access:https://www.mdpi.com/1422-0067/20/16/3939