Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes

Adaptation and Therapeutic Exploitation of the Plasma Membrane of African Trypanosomes

African trypanosomes are highly divergent from their metazoan hosts, and as part of adaptation to a parasitic life style have developed a unique endomembrane system. The key virulence mechanism of many pathogens is successful immune evasion, to enable survival within a host, a feature that requires...

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Bibliographic Details
Main Authors: Juan F. Quintana, Ricardo Canavate Del Pino, Kayo Yamada, Ning Zhang, Mark C. Field
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Genes
Subjects:
Trypanosoma brucei
surface proteome
endomembrane system
endocytosis
drug development
nanobodies
Online Access:http://www.mdpi.com/2073-4425/9/7/368

Internet

http://www.mdpi.com/2073-4425/9/7/368

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