The Role of Dicer in DNA Damage Repair

Dicer is the key component of the RNA interference pathway. Our group and others have reported that knockdown or knockout of Dicer leads to DNA damage in mammalian cells. Two groups recently showed that efficiency of DNA damage repair was greatly reduced in Dicer-deficient cells and that Dicer-depen...

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Bibliographic Details
Main Authors: Kai-Fu Tang, Hong Ren
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/13/12/16769