Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells.

Because endothelial nitric oxide synthase (eNOS) has anti-inflammatory and anti-arteriosclerotic functions, it has been recognized as one of the key molecules essential for the homeostatic control of blood vessels other than relaxation of vascular tone. Here, we examined whether telmisartan modulate...

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Bibliographic Details
Main Authors: Masahiro Myojo, Daisuke Nagata, Daishi Fujita, Arihiro Kiyosue, Masao Takahashi, Hiroshi Satonaka, Yoshiyuki Morishita, Tetsu Akimoto, Ryozo Nagai, Issei Komuro, Yasunobu Hirata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020804?pdf=render