Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures

<p>Abstract</p> <p>Background</p> <p>Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resi...

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Bibliographic Details
Main Authors: Bergstrom Carl T, Lipsitch Marc, Antia Rustom
Format: Article
Language:English
Published: BMC 2003-01-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/4/2