The Effect of Rosmarinic Acid on Apoptosis and nNOS Immunoreactivity Following Intrahippocampal Kainic Acid Injections in Rats

The Effect of Rosmarinic Acid on Apoptosis and nNOS Immunoreactivity Following Intrahippocampal Kainic Acid Injections in Rats

Introduction: Kainic Acid (KA) is an ionotropic glutamate receptor agonist. KA can induce neuronal overactivity and excitotoxicity. Rosmarinic Acid (RA) is a natural polyphenolic compound with antioxidant, anti-apoptotic, anti-neurodegenerative, and anti-inflammatory properties. This study aimed to...

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Bibliographic Details
Main Authors: Safoura Khamse, Seyed Shahabeddin Sadr, Mehrdad Roghani, Mina Rashvand, Maryam Mohammadian, Narges Marefati, Elham Harati, Fatemeh Ebrahimi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2020-01-01
Series:Basic and Clinical Neuroscience
Subjects:
kainic acid
rosmarinic acid
nnos-positive neurons
tunel-positive cells
mapk and cox-2 immunoreactivity
Online Access:http://bcn.iums.ac.ir/article-1-753-en.html

Internet

http://bcn.iums.ac.ir/article-1-753-en.html

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