JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells

JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells

JC polyomavirus (JCPyV) is a ubiquitous human pathogen that causes progressive multifocal leukoencephalopathy (PML), a severe and often fatal neurodegenerative disease in immunocompromised or immunomodulated patients. The mechanisms responsible for initiating infection in susceptible cells are not c...

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Bibliographic Details
Main Authors: Jenna Morris-Love, Gretchen V. Gee, Bethany A. O’Hara, Benedetta Assetta, Abigail L. Atkinson, Aisling S. Dugan, Sheila A. Haley, Walter J. Atwood
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
progressive multifocal leukoencephalopathy
central nervous system infections
extracellular vesicle
polyomavirus
virus receptor
Online Access:https://doi.org/10.1128/mBio.00379-19

Internet

https://doi.org/10.1128/mBio.00379-19

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