Neuropeptide regulation of adaptive immunity in the tibia fracture model of complex regional pain syndrome

Neuropeptide regulation of adaptive immunity in the tibia fracture model of complex regional pain syndrome

Abstract Background Both dysfunctional neuropeptide signaling and immune system activation are characteristic of complex regional pain syndrome (CRPS). Unknown is whether substance P (SP) or calcitonin gene-related peptide (CGRP) support autoantibody production and, consequently, nociceptive sensiti...

Full description

Bibliographic Details
Main Authors: Wen-Wu Li, Tian-Zhi Guo, Xiaoyou Shi, Frank Birklein, Tanja Schlereth, Wade S. Kingery, J. David Clark
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Neuroinflammation
Subjects:
Complex regional pain syndrome
Adaptive immunity
Neuropeptide
Substance P
Calcitonin gene-related peptide
Fracture
Online Access:http://link.springer.com/article/10.1186/s12974-018-1145-1

Internet

http://link.springer.com/article/10.1186/s12974-018-1145-1

Similar Items