Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

Abstract Background Claudin-low breast cancer is a molecular subtype associated with poor prognosis and without targeted treatment options. The claudin-low subtype is defined by certain biological characteristics, some of which may be clinically actionable, such as high immunogenicity. In mice, the...

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Bibliographic Details
Main Authors: Christian Fougner, Helga Bergholtz, Raoul Kuiper, Jens Henrik Norum, Therese Sørlie
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Claudin-low
Subtypes
Genomics
Transcriptomics
Mouse models
Online Access:http://link.springer.com/article/10.1186/s13058-019-1170-8

Internet

http://link.springer.com/article/10.1186/s13058-019-1170-8

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