PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder

Alcohol use disorder (AUD) is a chronic relapsing disorder characterized by an impaired ability to control or stop alcohol intake and is associated with organ damage including alcohol-associated liver disease (ALD) and progressive neurodegeneration. The etiology of AUD is complex, but organ injury d...

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Bibliographic Details
Main Authors: Ji Soo Lee, Emma M. O’Connell, Pal Pacher, Falk W. Lohoff
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
AUD
ALD
Online Access:https://www.mdpi.com/2077-0383/10/8/1758