A novel patient-derived intra-femoral xenograft model of bone metastatic prostate cancer that recapitulates mixed osteolytic and osteoblastic lesions

A novel patient-derived intra-femoral xenograft model of bone metastatic prostate cancer that recapitulates mixed osteolytic and osteoblastic lesions

<p>Abstract</p> <p/> <p>Prostate cancer metastasizes to bone in the majority of patients with advanced disease leading to painfully debilitating fractures, spinal compression and rapid decline. In addition, prostate cancer bone metastases often become resistant to standard th...

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Bibliographic Details
Main Authors: Raheem Omer, Kulidjian Anna A, Wu Christina, Jeong Young B, Yamaguchi Tomonori, Smith Kristen M, Goff Daniel, Leu Heather, Morris Sheldon R, Cacalano Nicholas A, Masuda Koichi, Jamieson Catriona HM, Kane Christopher J, Jamieson Christina AM
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/185

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http://www.translational-medicine.com/content/9/1/185

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