Impact of tumor cell cytoskeleton organization on invasiveness and migration: a microchannel-based approach.

Cell migration is a fundamental feature of the interaction of cells with their surrounding. The cell's stiffness and ability to deform itself are two major characteristics that rule migration behavior especially in three-dimensional tissue. We simulate this situation making use of a micro-fabri...

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Bibliographic Details
Main Authors: Claudio G Rolli, Thomas Seufferlein, Ralf Kemkemer, Joachim P Spatz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806915?pdf=render