Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube.

Pattern formation in developing tissues is driven by the interaction of extrinsic signals with intrinsic transcriptional networks that together establish spatially and temporally restricted profiles of gene expression. How this process is orchestrated at the molecular level by genomic cis-regulatory...

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Bibliographic Details
Main Authors: Steven Moore, Vanessa Ribes, Javier Terriente, David Wilkinson, Frédéric Relaix, James Briscoe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3789833?pdf=render