Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells.

Glioblastoma multiforme (GBM)-initiating cells (GICs) represent a tumor subpopulation with neural stem cell-like properties that is responsible for the development, progression and therapeutic resistance of human GBM. We have recently shown that blockade of NFκB pathway promotes terminal differentia...

Full description

Bibliographic Details
Main Authors: Beatriz Aldaz, Ainara Sagardoy, Lorena Nogueira, Elizabeth Guruceaga, Lara Grande, Jason T Huse, Maria A Aznar, Ricardo Díez-Valle, Sonia Tejada-Solís, Marta M Alonso, Jose L Fernandez-Luna, Jose A Martinez-Climent, Raquel Malumbres
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796557?pdf=render