Modelling Proteasome and Proteasome Regulator Activities
Proteasomes are key proteases involved in a variety of processes ranging from the clearance of damaged proteins to the presentation of antigens to CD8+ T-lymphocytes. Which cleavage sites are used within the target proteins and how fast these proteins are degraded have a profound impact on immune sy...
Main Authors: | Juliane Liepe, Herman-Georg Holzhütter, Peter M. Kloetzel, Michael P. H. Stumpf, Michele Mishto |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-06-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-273X/4/2/585 |
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