Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions

Effect of Bucillamine on Free-Radical-Mediated Degradation of High-Molar-Mass Hyaluronan Induced in vitro by Ascorbic Acid and Cu(II) Ions

The bucillamine effect on free-radical-mediated degradation of high-molar-mass hyaluronan (HA) has been elucidated. As HA fragmentation is expected to decrease its dynamic viscosity, rotational viscometry was applied to follow the oxidative HA degradation. Non-isothermal chemiluminometry, thermograv...

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Bibliographic Details
Main Authors: Mária Baňasová, Katarína Valachová, Jozef Rychlý, Ivica Janigová, Katarína Csomorová, Raniero Mendichi, Danica Mislovičová, Ivo Juránek, Ladislav Šoltés
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Polymers
Subjects:
disease-modifying antirheumatic drugs
rotational viscometry
size exclusion chromatography
thermo-analytical methods
Online Access:http://www.mdpi.com/2073-4360/6/10/2625

Internet

http://www.mdpi.com/2073-4360/6/10/2625

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