Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer

Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer

Purpose: Aggressively growing tumors are characterized by significant variations in metabolites, including lipids, and can involve the elevated synthesis ofde novo fatty acids. Methods: Ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS)-based metabolomics and lipidomics we...

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Bibliographic Details
Main Authors: Qianqian Sun, Xiaojuan Yu, Chunwei Peng, Ning Liu, Wentong Chen, Hu Xu, Hongquan Wei, Kun Fang, Ziwei Dong, Chuyu Fu, Youzhi Xu, Wenjie Lu
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Lipidomics
Gastric cancer
SREBP-1c
Palmitic acid
Cancer therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220304662

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http://www.sciencedirect.com/science/article/pii/S0753332220304662

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