Selenoxide Elimination Triggers Enamine Hydrolysis to Primary and Secondary Amines: A Combined Experimental and Theoretical Investigation

Selenoxide Elimination Triggers Enamine Hydrolysis to Primary and Secondary Amines: A Combined Experimental and Theoretical Investigation

We discuss a novel selenium-based reaction mechanism consisting in a selenoxide elimination-triggered enamine hydrolysis. This one-pot model reaction was studied for a set of substrates. Under oxidative conditions, we observed and characterized the formation of primary and secondary amines as elimin...

Full description

Bibliographic Details
Main Authors: Giovanni Ribaudo, Marco Bortoli, Erika Oselladore, Alberto Ongaro, Alessandra Gianoncelli, Giuseppe Zagotto, Laura Orian
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
selenoxide elimination
one-pot
imine-enamine
reaction mechanism
DFT calculations
selenium
Online Access:https://www.mdpi.com/1420-3049/26/9/2770

Internet

https://www.mdpi.com/1420-3049/26/9/2770

Similar Items