Phase I dose-escalation oncology trials with sequential multiple schedules

Abstract Background Conventional methods for phase I dose-escalation trials in oncology are based on a single treatment schedule only. More recently, however, multiple schedules are more frequently investigated in the same trial. Methods Here, we consider sequential phase I trials, where the trial p...

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Bibliographic Details
Main Authors: Burak Kürsad Günhan, Sebastian Weber, Abdelkader Seroutou, Tim Friede
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-021-01218-9