Complement effectors, C5a and C3a, in cystic fibrosis lung fluid correlate with disease severity.

In cystic fibrosis (CF), lung damage is mediated by a cycle of obstruction, infection, inflammation and tissue destruction. The complement system is a major mediator of inflammation for many diseases with the effectors C5a and C3a often playing important roles. We have previously shown in a small pi...

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Bibliographic Details
Main Authors: Pamela S Hair, Laura A Sass, Turaj Vazifedan, Tushar A Shah, Neel K Krishna, Kenji M Cunnion
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5344399?pdf=render