Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC

Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC

Parkinson’s disease (PD) is a progressive neurodegenerative disease which is histologically characterized by loss of dopaminergic neurons in the substantia nigra and deposition of aggregated alpha‐synuclein (aSyn) in the brain. The detection of aSyn in well accessible fluids has been one of the cent...

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Bibliographic Details
Main Authors: Viktoria C. Ruf, Song Shi, Felix Schmidt, Daniel Weckbecker, Georg S. Nübling, Uwe Ködel, Brit Mollenhauer, Armin Giese
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:FEBS Open Bio
Subjects:
(q)RT‐QuIC
aggregation
alpha‐synuclein
biomarker
Parkinson’s disease
seeding
Online Access:https://doi.org/10.1002/2211-5463.12844

Internet

https://doi.org/10.1002/2211-5463.12844

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