Test-retest reproducibility of [11C]-l-deprenyl-D2 binding to MAO-B in the human brain

Test-retest reproducibility of [11C]-l-deprenyl-D2 binding to MAO-B in the human brain

Abstract Background [11C]-l-deprenyl-D2 is a positron emission tomography (PET) radioligand for measurement of the monoamine oxidase B (MAO-B) activity in vivo brain. The estimation of the test-retest reproducibility is important for accurate interpretation of PET studies. Results We performed two [...

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Bibliographic Details
Main Authors: Ryosuke Arakawa, Per Stenkrona, Akihiro Takano, Sangram Nag, Rafael S. Maior, Christer Halldin
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:EJNMMI Research
Subjects:
Age effect
[11C]-l-deprenyl-D2
Monoamine oxidase B
Partial volume effect correction
Positron emission tomography
Test-retest variability
Online Access:http://link.springer.com/article/10.1186/s13550-017-0301-4

Internet

http://link.springer.com/article/10.1186/s13550-017-0301-4

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