Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen

Cancer stem cells (CSCs) can act as the cellular drivers of tumors harnessing stem cell properties that contribute to tumorigenesis either as founder elements or by the gain of stem cell traits by the malignant cells. Thus, CSCs can self-renew and generate the cellular heterogeneity of tumors includ...

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Bibliographic Details
Main Authors: Richard Harrop, Eric O’Neill, Peter L. Stern
Format: Article
Language:English
Published: SAGE Publishing 2019-01-01
Series:Therapeutic Advances in Vaccines and Immunotherapy
Online Access:https://doi.org/10.1177/2515135518821623