Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells

Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells

Reynoutria multiflora (Thunb.) Moldenke (He Shou Wu) has been used for about 20 centuries as a Chinese medicinal herb for its activities of anticancer, anti-hyperlipidemia, and anti-aging. Previously, we found that He Shou Wu ethanol extract could induce apoptosis in hepatocellular carcinoma cells,...

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Bibliographic Details
Main Authors: Nian Yang, Chen Li, Hongliang Li, Ming Liu, Xiaojun Cai, Fengjun Cao, Yibin Feng, Minglun Li, Xuanbin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
emodin
lipid metabolism
SREBP1
intrinsic apoptosis
hepatocellular carcinoma cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00709/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00709/full

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