Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88

Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88

Summary: Normal dynamics between microbiota and dendritic cells (DCs) support modest numbers of T cells, yet these do not cause inflammation. The DCs that induce inflammatory T cells and the signals that drive this process remain unclear. Here, we demonstrate that small intestine DCs lacking the sig...

Full description

Bibliographic Details
Main Authors: Jie Liang, Hsin-I Huang, Fernanda P. Benzatti, Amelia B. Karlsson, Junyi J. Zhang, Nourhan Youssef, Averil Ma, Laura P. Hale, Gianna E. Hammer
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716313675

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716313675

Similar Items