Engineering Elastic Nano- and Micro-Patterns and Textures for Directed Cell Motility

Summary: We present a reproducible protocol for fabrication of polyacrylamide (PAA) hydrogel-based nano-patterns and nano-textures with a wide range of elastic rigidities to study fundamental cell behaviors, such as mechanosensitivity and motility. We explore the benefits of this protocol by success...

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Bibliographic Details
Main Authors: Erdem D. Tabdanov, Alexander S. Zhovmer, Vikram Puram, Paolo P. Provenzano
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:STAR Protocols
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166719300139