Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila

Three-dimensional eukaryotic genome organization provides the structural basis for gene regulation. In Drosophila melanogaster, genome folding is characterized by somatic homolog pairing, where homologous chromosomes are intimately paired from end to end; however, how homologs identify one another a...

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Bibliographic Details
Main Authors: Myron Barber Child VI, Jack R Bateman, Amir Jahangiri, Armando Reimer, Nicholas C Lammers, Nica Sabouni, Diego Villamarin, Grace C McKenzie-Smith, Justine E Johnson, Daniel Jost, Hernan G Garcia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/64412