KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation

KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation

Abstract Background Histone lysine demethylase 4B (KDM4B) has been implicated in various pathological processes and human diseases. Glucose metabolism is the main pattern of energy supply in cells and its dysfunction is closely related to tumorigenesis. Recent study shows that KDM4B protects against...

Full description

Bibliographic Details
Main Authors: Haijie Li, Jingqin Lan, Guihua Wang, Kaixuan Guo, Caishun Han, Xiaolan Li, Junbo Hu, Zhixin Cao, Xuelai Luo
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
KDM4B
GLUT1
AKT activation
TRAF6
Glucose metabolism
Online Access:https://doi.org/10.1186/s13046-020-1522-3

Internet

https://doi.org/10.1186/s13046-020-1522-3

Similar Items