Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling

Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling

Abstract Background Ovarian cancer is the fifth leading cause of cancer-related deaths amongst women in the United States. Cachexia is the primary cause of death in approximately 30% of cancer patients, and is often evidenced in ovarian cancer patients. We tested the steroidal lactone Withaferin A t...

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Bibliographic Details
Main Authors: Alex R. Straughn, Sham S. Kakar
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Ovarian Research
Subjects:
Cachexia
Cancer
Ovarian Cancer
Skeletal muscle
NF-κB
Inflammation
Online Access:http://link.springer.com/article/10.1186/s13048-019-0586-1

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http://link.springer.com/article/10.1186/s13048-019-0586-1

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