Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans

2-Methylacyl-CoA racemase is an auxiliary enzyme required for the peroxisomal β-oxidative breakdown of (2R)-pristanic acid and the (25R)-isomer of C27 bile acid intermediates. The enzyme activity is found not only in peroxisomes but also is present in mitochondria of human liver and fibroblasts. The...

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Bibliographic Details
Main Authors: Leen Amery, Mark Fransen, Katelijne De Nys, Guy P. Mannaerts, Paul P. Van Veldhoven
Format: Article
Language:English
Published: Elsevier 2000-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319684