Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans
2-Methylacyl-CoA racemase is an auxiliary enzyme required for the peroxisomal β-oxidative breakdown of (2R)-pristanic acid and the (25R)-isomer of C27 bile acid intermediates. The enzyme activity is found not only in peroxisomes but also is present in mitochondria of human liver and fibroblasts. The...
Main Authors: | Leen Amery, Mark Fransen, Katelijne De Nys, Guy P. Mannaerts, Paul P. Van Veldhoven |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2000-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520319684 |
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