Santamarine Shows Anti-Photoaging Properties via Inhibition of MAPK/AP-1 and Stimulation of TGF-β/Smad Signaling in UVA-Irradiated HDFs

Santamarine Shows Anti-Photoaging Properties via Inhibition of MAPK/AP-1 and Stimulation of TGF-β/Smad Signaling in UVA-Irradiated HDFs

Chronic UVA exposure results in elevated reactive oxygen species in skin which leads to photoaging characterized as upregulated matrix metalloproteinase (MMP)-1 and loss of collagen. Therefore, natural antioxidants are hailed as promising agents to be utilized against photoaging. In the current stud...

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Bibliographic Details
Main Authors: Jung Hwan Oh, Junse Kim, Fatih Karadeniz, Hye Ran Kim, So Young Park, Youngwan Seo, Chang-Suk Kong
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
human dermal fibroblast
MAPK
photoaging
reynosin
santamarine
TGF-β
Online Access:https://www.mdpi.com/1420-3049/26/12/3585

Internet

https://www.mdpi.com/1420-3049/26/12/3585

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