A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

Summary: Many tumors are hierarchically organized with a minority cell population that has stem-like properties and enhanced ability to initiate tumorigenesis and drive therapeutic relapse. These cancer stem cells (CSCs) are typically identified by complex combinations of cell-surface markers that d...

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Bibliographic Details
Main Authors: Binwu Tang, Asaf Raviv, Dominic Esposito, Kathleen C. Flanders, Catherine Daniel, Bao Tram Nghiem, Susan Garfield, Langston Lim, Poonam Mannan, Ana I. Robles, William I. Smith, Jr., Joshua Zimmerberg, Rea Ravin, Lalage M. Wakefield
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111400352X