Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma

Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma

The activation of Toll-like receptor (TLR) signaling is widely reported to be involved in preventing the development of allergic asthma. However, the mechanism of the protective function of TLR signaling remains limited. Here, we studied the mouse model of ovalbumin (OVA)-induced allergic asthma and...

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Bibliographic Details
Main Authors: Chao Huang, Jian Wang, Xiaodong Zheng, Yongyan Chen, Haiming Wei, Rui Sun, Zhigang Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
allergic asthma
TLR signaling
inflammatory monocytes
Th1-associated cytokines
sensitization
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02591/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02591/full

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