Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies.

Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL). The aim of our study was to investigate whether the routinely administered ALL chemotherapeutic agents would be able to bind an...

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Bibliographic Details
Main Authors: Archana Jayaraman, Kaiser Jamil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893288?pdf=render