New insights into how trafficking regulates T cell receptor signaling

New insights into how trafficking regulates T cell receptor signaling

AbstractThere is emerging evidence that exocytosis plays an important role in regulating T cell receptor (TCR) signaling. The trafficking molecules involved in lytic granule (LG) secretion in cytotoxic T lymphocytes (CTL) have been well studied due to the immune disorder known as familial hemophagoc...

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Bibliographic Details
Main Authors: Jieqiong Lou, Jeremie Rossy, Qiji Deng, Sophie Victoria Pageon, Katharina Gaus
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Rabs
SNAREs
LAT
TCR signaling
Exocytic trafficking
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00077/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00077/full

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