An improved method for scoring protein-protein interactions using semantic similarity within the gene ontology

<p>Abstract</p> <p>Background</p> <p>Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based on their function using annotation systems like the Gene Ontology (...

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Bibliographic Details
Main Authors: Jain Shobhit, Bader Gary D
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/562