SOX2-Upregulated microRNA-30e Promotes the Progression of Esophageal Cancer via Regulation of the USP4/SMAD4/CK2 Axis

SOX2-Upregulated microRNA-30e Promotes the Progression of Esophageal Cancer via Regulation of the USP4/SMAD4/CK2 Axis

Esophageal cancer (EC) is a highly aggressive disease, and its progression involves a complex gene regulation network. Transcription factor SOX2 is amplified in various cancers including EC. A pathway involving SOX2 regulation of microRNAs (miRNAs) and their target genes has been previously revealed...

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Bibliographic Details
Main Authors: Yang Yang, Xin Fan, Yukai Ren, Kai Wu, Xiangyu Tian, Fengbiao Wen, Donglei Liu, Yuxia Fan, Song Zhao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
esophageal cancer
SOX2
microRNA-30e
USP4
SMAD4
CK2
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303395

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http://www.sciencedirect.com/science/article/pii/S2162253120303395

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